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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH6
All Species:
27.27
Human Site:
T1008
Identified Species:
42.86
UniProt:
P52701
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52701
NP_000170.1
1360
152786
T1008
K
G
C
K
R
Y
W
T
K
T
I
E
K
K
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113749
1360
152750
T1008
K
G
C
K
R
Y
W
T
K
T
I
E
K
K
L
Dog
Lupus familis
XP_531814
1283
145094
W969
F
D
K
N
Y
K
D
W
Q
S
A
V
E
C
I
Cat
Felis silvestris
Mouse
Mus musculus
P54276
1358
151058
T1005
K
G
C
K
R
Y
W
T
K
T
I
E
K
K
L
Rat
Rattus norvegicus
XP_002726765
1361
151628
T1008
K
G
C
K
R
Y
W
T
K
V
I
E
K
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419359
1466
164165
T1114
K
G
Y
K
R
Y
W
T
K
E
I
E
K
M
L
Frog
Xenopus laevis
NP_001089247
1340
149481
T988
K
G
F
K
R
Y
W
T
K
A
I
E
K
M
F
Zebra Danio
Brachydanio rerio
NP_878280
1369
153213
T1009
K
G
W
K
R
Y
S
T
K
D
I
E
R
M
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUM0
1190
133117
W883
F
S
N
H
Y
D
Q
W
K
Q
C
I
D
C
V
Honey Bee
Apis mellifera
XP_392346
1120
127429
L813
R
D
K
V
L
K
D
L
N
R
R
I
F
A
Q
Nematode Worm
Caenorhab. elegans
NP_491163
1186
133609
L879
G
H
K
N
P
I
W
L
E
T
V
K
L
V
S
Sea Urchin
Strong. purpuratus
XP_797647
1335
149141
S980
K
G
F
K
R
Y
W
S
P
T
I
Q
N
L
L
Poplar Tree
Populus trichocarpa
XP_002320307
1288
142120
A973
L
D
V
L
I
S
L
A
I
A
S
D
F
Y
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04716
1324
146779
P962
G
V
S
R
Y
W
T
P
T
I
K
K
L
L
K
Baker's Yeast
Sacchar. cerevisiae
Q03834
1242
140062
T935
V
D
E
V
D
S
K
T
N
T
Q
L
N
G
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.3
88.1
N.A.
85.8
86.4
N.A.
N.A.
64.2
66.5
60
N.A.
39
41.2
34.4
48.6
Protein Similarity:
100
N.A.
98.6
91.3
N.A.
92.1
92.8
N.A.
N.A.
75.4
79.9
74.9
N.A.
57.6
58
52.7
66.6
P-Site Identity:
100
N.A.
100
0
N.A.
100
93.3
N.A.
N.A.
80
73.3
60
N.A.
6.6
0
13.3
60
P-Site Similarity:
100
N.A.
100
26.6
N.A.
100
93.3
N.A.
N.A.
80
73.3
66.6
N.A.
13.3
6.6
33.3
73.3
Percent
Protein Identity:
36.1
N.A.
N.A.
33.2
29
N.A.
Protein Similarity:
52
N.A.
N.A.
51.4
49.1
N.A.
P-Site Identity:
0
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
0
14
7
0
0
7
0
% A
% Cys:
0
0
27
0
0
0
0
0
0
0
7
0
0
14
0
% C
% Asp:
0
27
0
0
7
7
14
0
0
7
0
7
7
0
0
% D
% Glu:
0
0
7
0
0
0
0
0
7
7
0
47
7
0
7
% E
% Phe:
14
0
14
0
0
0
0
0
0
0
0
0
14
0
20
% F
% Gly:
14
54
0
0
0
0
0
0
0
0
0
0
0
7
0
% G
% His:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
7
0
0
7
7
54
14
0
0
7
% I
% Lys:
54
0
20
54
0
14
7
0
54
0
7
14
40
27
7
% K
% Leu:
7
0
0
7
7
0
7
14
0
0
0
7
14
14
40
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% M
% Asn:
0
0
7
14
0
0
0
0
14
0
0
0
14
0
0
% N
% Pro:
0
0
0
0
7
0
0
7
7
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
7
0
7
7
7
7
0
0
7
% Q
% Arg:
7
0
0
7
54
0
0
0
0
7
7
0
7
0
0
% R
% Ser:
0
7
7
0
0
14
7
7
0
7
7
0
0
0
7
% S
% Thr:
0
0
0
0
0
0
7
54
7
40
0
0
0
0
0
% T
% Val:
7
7
7
14
0
0
0
0
0
7
7
7
0
7
7
% V
% Trp:
0
0
7
0
0
7
54
14
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
20
54
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _